The results are pretty straightforward: for any combination you can think of (running when young, running when old, running throughout life, etc.), the runners were less likely to develop arthritis than non-runners, by between 16 and 29 percent. Some of this was because of the fact that runners tend to weigh less – which is, indeed, one of the benefits of running – but even when the results were adjusted to account for that difference, the runners still came out ahead.
This data still isn’t perfect, but it adds another brick to the growing pile suggesting that running will not ruin your knees. In contrast, a similar analysis of data from the same Osteoarthritis Initiative, published last year, found that acute knee injuries were associated with more rapid progression of osteoarthritis. That’s consistent with earlier studies suggesting that increased risk of knee arthritis among former athletes is pretty much entirely explained by acute injuries. If you want to save your knees, in other words, worry more about twisting them than pounding them.